IL1B and neoplasm: Such a dysregulated native microbiome triggers myeloid differentiation factor 88 (Myd88)-dependent production of IL-1 and IL-23 and induces the activation and proliferation of pulmonary resident Vγ6 + Vδ1 + γδ T cells.200 The microbiota takes advantage of the pulmonary microenvironment of immunity to foster neoplasm growth and disease development.