TNF and pneumoconiosis: Intraperitoneal injection of indole-3-acetic acid into emphysema model mice reduced the decreases in lung function, emphysema, tissue damage, collagen deposition, and levels of TNF-α, IL-1β, IL-6, and IL-17A.223 By comparing the differences in sputum bacteria between pneumoconiosis patients and controls, scientists found an increased percentage of Streptococcus, Granuliococcus, and Bacillus in pneumoconiosis patients.