Further, we included several explorative analyses to investigate the associations between biomarkers (Aβ40, Aβ38, sAPPα, sAPPβ, t-tau, p-tau, p-tau /t-tau, NF-L and NG in CSF, Aβ42, Aβ40, Aβ42/38, Aβ42/40, t-tau, p-tau, p-tau /t-tau and NF-L in plasma and S100B in serum) and cognitive function (global cognition, verbal memory, psychomotor speed, sustained attention, and executive function) in BD and HC jointly. This evidence concerns the gene NEFL and Behcet disease.