In order to explore whether LRP6 might affect tumor progression through the regulation of ferroptosis, we analyzed the correlation between LRP6 and the expression of 25 common ferroptosis related genes in renal clear cell carcinoma samples, and found that LRP6 was significantly correlated with most ferroptosis related genes except for SAT1, MT1G, and SLC1A5 genes (Figure 7). The gene discussed is LRP6; the disease is clear cell renal carcinoma.