At the same time, a study conducted by Chen et al. on the 14-3-3 protein and T-Tau protein in the cerebrospinal fluid of Chinese patients with gPrD showed that 41.47% of FFI patients had Tau protein less than 2000 pg/ml, and T-Tau content in CSF of FFI patients with myoclonus is relatively high [20]. This evidence concerns the gene MAPT and Myoclonus.