MAF1 and Optic neuropathy: 25 Additionally, a previous study demonstrated the neuroprotective effect of Maf1 on survival after root ganglion cell injury and provided a potential treatment strategy for traumatic optic neuropathy.26 As a result, Maf1 has become a hot topic, and it is therefore now possible to further clarify the mechanism of synaptic remodelling by exploring the morphology and potential function of Maf1 in regulating neuronal synapses.