A study from the COVID Human Genetic Effort (https://www.covidhge.com) analyzed a sample of 659 individuals with life-threatening COVID-19 and observed that at least 23 (3.5%) of the patients had loss-of-function mutations in 8 out of 13 tested loci (IRF3, IRF7, IFNAR1, IFNAR2, TLR3, TICAM1, TBK1, and UNC93B1) (Zhang et al., 2020b). Here, IFNAR1 is linked to COVID-19.