Encouragingly, based on similarities between CFTR (ABCC7) — itself an ABC transporter protein (60) and the causal gene for cystic fibrosis (61–63) — and ABCA3, recent studies have repurposed drugs developed to modulate CFTR function for restoration of ABCA3 function in cancer cell line models. The gene discussed is ABCG2; the disease is cystic fibrosis.