PVT1 and liver cancer: LncRNA plasmacytoma variant translocation 1 (PVT1) is associated with the development and progression of cancers. Functional studies on HCC cell line SMMC-7721 demonstrated that lncRNA PVT1 may promote liver cancer progression by inhibiting histone methylation on the MYC promoter, signifying it as potential target for therapeutic strategies of the malignancy.