PRES-SLE patients had a higher value of cytokine levels (IL-6 and IL-10) as compared to other patients. There was no correlation between cytokine levels with MRI abnormalities and PRES remission. PRES had no significant effect on other cytokine levels and CD40L and VEGF. The gene discussed is CD40LG; the disease is Posterior Leukoencephalopathy Syndrome.