STAT3 and autoimmune thrombocytopenic purpura: Previous studies have investigated the role of lncRNAs in regulating the functions and differentiation of lymphocytes and hence their role in the pathology of ITP.[45, 46] LncRNAs act through targeted genes to mediate their actions and influence the development of ITP.[47] For example, targeting STAT3 by lncDC affected the differentiation of dendritic cells, which then induced the activation of the immune response.[48, 49] However, the exact molecular mechanisms of many lncRNAs in ITP remain unclear.