It is also interesting to notice that among the few examples of circRNAs which encode proteins, most have anti-tumor effects: circLINC-PINT has been reported to produce PINT87aa that suppresses glioblastoma38; FBXW7-185aa produced from circFBXW7 mentioned above is known to inhibit cancer proliferation and migration39; circPPP1R12A-73aa from circPPP1R12A was found to display a tumor suppressive role in colon cancer40. The gene discussed is LINC-PINT; the disease is cancer.