In contrast to more preneoplastic nodules at 2 weeks (Fig. 7B, C) and more tumors and proliferative hepatocytes at 4 weeks after active c-Jun expression (Fig. 7D–G), simultaneous overexpression of ZBTB7B completely abolished the tumor-promoting effects of active c-Jun (Fig. 7). Here, ZBTB7B is linked to neoplasm.