All three ALS donors had an SOD1 mutation (donor 1: D102H mutation; donor 2: A4V; donor 2: V87A), and all three donors did not have a C9orf72 repeat expansion.These three donors succumbed to ALS at 42 (female), 55 (male), or 58 (male) years of age. This evidence concerns the gene SOD1 and amyotrophic lateral sclerosis.