BRCA1 and metastatic malignant neoplasm in the lymph nodes: Additionally, patients with high BRCA1 expression had worse outcomes in subgroups with different tumor sizes (specifically T1 and T2, T3 and T2), absence and presence of lymph node metastasis (N0 and N1), age older than 60 years, patients with invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC) (Figure 5).