On a molecular level, frontotemporal lobar degeneration can be differentiated into three different subtypes based on abnormal protein deposition: tau (tau protein), transactive response DNA-binding protein with molecular weight 43 kDa (TDP-43), and FET (fused-in-sarcoma [FUS] and Ewing sarcoma [EWS] proteins, and TATA-binding protein-associated factor 15 [TAF15]) (Bang et al., 2015; Haass and Neumann, 2016). Here, MAPT is linked to frontotemporal dementia.