Supervised hierarchical clustering of Illumina methylation data identified three differentially methylated probes within MGMT: Two probes (cg12434587 and cg12981137) were congruent with prior reports in GBM patient samples using the MGMT-STP27 logistic regression model [33], localized to the promoter, correlating with patient outcomes; the third probe (cg01341123), upstream to Region 1, has not been previously reported as a survival correlate. Here, MGMT is linked to glioblastoma.