These results indicated that ARID5B‐mediated LINC01128 regulated pyroptosis and apoptosis via the BTF3/p‐STAT3 axis, exacerbating inflammation and thrombosis in mice with APS, and that OICR‐9429 could relieve APS progression by blocking the above pathways (Figure 7L). Here, BTF3 is linked to autoimmune polyendocrinopathy.