ClinicalTrials.gov records more than 1000 published clinical trials that tested anti‐PD‐1/PD‐L1 antibodies in >100 000 patients with cancer between 2010 and 2020.[177] FDA Adverse Event Reporting System (FAERS) is a public database that stores spontaneous reports on IRAEs related to FDA‐approved products, which has been widely used to study drug response and IRAEs. This evidence concerns the gene CD274 and cancer.