Although intratumoal TILs showed marginal increases in CRC patients with higher peritumoral TILs, these did not reach statistical significance (CD3+TILsTCvs CD3+TILsIM, P = 0.535; CD3+TILsTCvs CD3+TILsTS, P = 0.240; CD8+TILsTCvs CD8+TILsIM, P = 0.093; CD8+TILsTCvs CD8+TILsTS, P = 0.058). This evidence concerns the gene CD8A and colorectal carcinoma.