The results depicted that the high expression of Bcl2 is associated with HER2-, ER+, PR+, Nodal negative, SBR1, NPI1, wild type P53, and non TNBC status (Fig. 2). The gene-gene interaction of Bcl2 showed that Bcl2 is highly correlated with Bcl2L11, FKBP8, BBC3 and other genes (Fig. 3). Using the UALCAN database, expression analysis of Bcl2 in relation to sample type, age group, BC subtypes, and ethnicity was further investigated. The gene discussed is BBC3; the disease is breast cancer.