TP53 and cancer: Bcl2 expression depicted heterogeneity in expression profile across the primary cancer cell population (Fig. 6). The PPI of Bcl2 revealed several genes interacting with Bcl2 and the top 10 hub genes include Bcl2, Bcl2L11, TP53, PMAIP1, BCL2L1, Bcl2L2, Bcl2A1, BIK, BAD, and BAK1 (Fig. 7).