Patients with young-onset (< 40 years) dystonia; exclusion of secondary etiologies, patients with a confirmed genetic dystonia based on single gene tests (TOR1A, SGCE, PRRT2, PANK2, GCH1, DRPLA, SCA1, 2, 3, 6, 7 & 17) and levodopa-responsive patients. The gene discussed is SGCE; the disease is Dystonia.