However, similar to 5ASA-fedmice, the expression of α-SMA and collagen-I in colitis tissuesin 40 mg/kg SA-treated mice (47% and 28.4%) and 80 mg/kg SA-treatedmice (85.6% and 83.7%) was appreciably lower than that in DSS-inducedmice (p < 0.05). The gene discussed is ACTA1; the disease is colitis.