This was accompanied by an increase in CD86 expression (Figure S2D, labeled as LPS/IT-sMSC-exo+αmiR) and a decrease in CD206 expression (Figure S2E, labeled as LPS/IT-sMSC-exo+αmiR) in the lung tissue of mice in the IT-sMSC-exo+αmiR group, suggesting the crucial role of miR-7704 in ALI treatment. This evidence concerns the gene MRC1 and acute respiratory distress syndrome.