BMI, body mass index; DM, diabetes mellitus; CRF, chronic renal failure; MI, myocardial infarction; ACEI, angiotensin-converting enzyme inhibitor; PCI, percutaneous coronary intervention; TIMI, thrombolysis in myocardial infarction; CRP, C-reactive protein; WMSI, wall motion score index; EF, ejection fraction; DV, diastolic volume; SV, systolic volume; MR, mitral regurgitation. The gene discussed is ACE; the disease is Mitral regurgitation.