FTH1 and Parkinson disease: The expression of FTH1 is significantly downregulated in 6-hydroyxdopamine-induced rat and PC-12 cell models of PD, and FTH1 has been found to induce ferroptosis through ferritinophagy, a type of autophagy that involves ferroptosis to degrade ferritin (Tian et al., 2020).