Classical DTDS is an infantile‐onset, progressive motor disorder, with symptoms including hyperkinesia, orolingual dyskinesia, parkinsonism‐dystonia and ocular flutter; atypical juvenile and adult‐onset forms are also reported with a less aggressive disease course, and associated with higher residual DAT function.18, 100, 101. The gene discussed is SLC6A3; the disease is SLC6A3-related dopamine transporter deficiency syndrome.