Secondly, although it was shown that KYN and QUNA levels were significantly higher in acute DILD patients than the various related lung diseases that were tested, and that their levels were not notably affected by underlying diseases, to further analyze the specificity of these biomarkers, their serum levels in other inflammatory diseases and viral diseases, in which IFN signaling pathways are activated, should be examined. Here, IFNA1 is linked to viral load.