Still, in the Lip Cancer and Squamous Cell Carcinoma, there was an increase in the amount of CD3+ (p < 0.001), CD8+ (p = 0.035), CD20+ (p < 0.001) and CD68+ (p < 0.001) cells within the tumor islands (intratumoral) (Table 1, Fig. 2). This evidence concerns the gene CD8A and lip cancer.