Considering that METTL14 induces NLRP3 mRNA m6A methylation and that the loss of m6A in NLRP3 mRNA mediated by METTL14 knockdown leads to a decrease in NLRP3 mRNA and protein expression in ALI mice, we sought to determine whether METTL14-mediated m6A modification affects the NLRP3 mRNA stability. Here, METTL14 is linked to acute respiratory distress syndrome.