Subsequently, we detected the expression of T cell-related markers (tcrα, tcrβ, cd8α, d8β, cd4-1,), B cell-related markers (igd, igm, igt), myeloid cell-related markers (ncf2, cd11b, mpeg1, and mpo), chemokines (ccr10, ccl20b, ccl9, cxcl13, and ccl25), as well as interleukins (il1β, il8, il10b, and il6) in the OM and found the expression of these immune-related genes also decreased significantly in the antibiotics treatment group (Fig. 4d). The gene discussed is CXCL13; the disease is ocular melanoma.