Figure 2B illustrates the network of Longya Lilium-fluoxetine-target constructed by Cytoscape software, and further functional enrichment analysis using the ClueGO plug-in suggested that the 6 genes were mainly enriched in intrinsic apoptotic signaling pathway in response to osmotic stress (GO:0008627), negative regulation of synaptic transmission, dopaminergic (GO:0032227) and Small cell lung cancer (KEGG:05222), of which COX-2 was at the core, and also enriched in the above functions (Fig. 2C, D). The gene discussed is PTGS2; the disease is small cell lung carcinoma.