As shown in Fig. 8B, C, compared with the Vector group, all two of these values were significantly decreased in the Tmprss6 group, and the results of hematoxylin and eosin staining in tumor sections showed that the Vector group tumors are quite dense, while the tumor structure in the Tmprss6 group was looser and with lighter nuclear staining (Supplementary Fig. S3). The gene discussed is TMPRSS6; the disease is neoplasm.