These include fusions of the ETV6 gene in secretory carcinoma (SC) [2–4], MYB/MYBL1::NFIB in adenoid cystic carcinoma (AdCC) [5], CRTC1/CRTC3::MAML2 in mucoepidermoid carcinoma (MEC) [6, 7], and EWSR1::ATF1 in hyalinizing clear cell carcinoma [8] as the most frequent and best characterized gene fusions (Table 1). The gene discussed is NFIB; the disease is adrenocortical carcinoma, hereditary.