XRCC1 and malignant colon neoplasm: Furthermore, we observed an increased phosphorylation level at the S241 locus within XRCC1 protein in breast cancer (P = 9.4E-13), colon cancer (P = 1.7E-34), GBM (P = 4.4E-02), UCEC (P = 7.4E-20), and ovarian cancer (P = 1.1E-08) (Figure 5B, 5D, 5F, 5G, 5I).