The patient cooperation score was relatively comparable between the groups for patients with NUC1–3 cataracts (score difference [95% CI] = − 010: [− 0.34, 0.14], p = 0.402) and for patients who received second-eye cataract surgery (score difference [95% CI] = − 0.15 [− 0.60, 0.30], p = 0.495). This evidence concerns the gene PPARD and cataract.