PRDM9 and Familial prostate cancer: Prostate cancer pathogenesis is also influenced by the roles of specific oncogenes and epigenetic regulators, including ERG (ETS-related gene), which is a member of the ETS family of transcription factors, known for roles in development and various cancers, including prostate cancer [9] and EZH2 (Enhancer of Zeste Homolog 2), which is a part of the Polycomb group of proteins, functioning as a histone methyltransferase and playing a crucial role in gene silencing and epigenetic regulation [10].