As shown in Table 3, age(HR = 1.05, P < 0.001), AVF as vascular access(HR 0.48, P = 0.002), Lp-PLA2 > 481.2 U/L (HR 2.15, P = 0.002), Lp-PLA2 activity (HR 1.18, P = 0.004), N-terminal pro b-type natriuretic peptide (NT-proBNP) (HR 2.08, P = 0.001), high sensitivity cardiac troponin T (hs-cTnT) (HR 7.30, P < 0.001), albumin (HR 0.94, P = 0.043), Serum creatinine (HR 0.99, P < 0.001), Uric acid (HR 0.99, P = 0.009), history of diabetes (HR 2.23, P = 0.001), history of CAD (HR 2.81, P < 0.001) were significantly associated with CV death. The gene discussed is NPPB; the disease is diabetes mellitus.