Age (HR 1.06, P < 0.001), AVF as vascular access(HR = 0.41, P < 0.001), Lp-PLA2 > 481.2 U/L (HR 1.81, P = 0.007), Lp-PLA2 (HR = 1.41, P = 0.018), NT-proBNP (HR 1.87, P = 0.004), hs-cTnT (HR 6.52, P < 0.001), albumin (HR = 0.94, P = 0.046), Serum creatinine (HR 0.99, P = 0.001), Uric acid (HR 0.99, P = 0.01), history of diabetes (HR 2.02, P = 0.002), history of CAD (HR 2.57, P = 0.001) were significantly associated with MACEs (Table 3). The gene discussed is PLA2G7; the disease is diabetes mellitus.