In addition, future studies should explore the comparative clinical utility of Lp-PLA2 between dialysis patients and those with non-dialysis CKD, and examine the trajectory of Lp-PLA2 in longitudinal studies, so as to understand the long-term implications of elevated Lp-PLA2 activity, particularly across different stages of CKD. The gene discussed is PLA2G7; the disease is chronic kidney disease.