Anti-IFN-γ autoantibodies (AIGAs) are considered susceptibility factors for infection by multiple intracellular pathogens, especially nontuberculous mycobacteria (NTM), Talaromyces marneffei, Cryptococcus neoformans, Histoplasma capsulatum [1, 2, 8]. The gene discussed is IFNG; the disease is infection.