The results showed that neither PBS, RGD nor RGD-p21Ras-scFv inhibited the growth of the normal colon epithelial cell line CCD841 (Fig. 3A); however, RGD-p21Ras-scFv significantly inhibited the growth of all the Ras-associated tumor cell lines we included (Fig. 3B L). This evidence concerns the gene HRAS and neoplasm.