HGF and liver disorder: Since HGF has been identified as modulator of liver fibrosis, which develops as sustained liver disease (Kwiecinski et al, 2011; Tekkesin et al, 2011), we propose that HGF-induced signal transduction determines the fate of hepatocytes and based on our results the extent of basal MET phosphorylation could be a central indicator facilitating the quantification of the alterations.