JCAD and coronary artery disorder: Using CAD GWAS summary statistics from a meta-analysis of the UK Biobank and CARDIoGRAMplusC4D51, we found the ADAMTS7 (P < 1.37e-3) and JCAD (P < 3.11e-4) networks in SMC to be significantly enriched (P < 0.05/29, adjusting for 29 networks) for CAD risk in the global analysis (Fig. 4a, Supplementary Fig. 17a, and Supplementary Data 13).