ECI2 and posterior cortical atrophy: Despite variability in their expression, this approach revealed several perFAO genes: ECI2, DECR2, ABCD1, CRAT, and ACOT8 (Fig. 1b) involved in regulation of fatty acid metabolism and energy homoeostasis that were consistently upregulated in both cohorts in metastatic tissues, suggesting an important role for perFAO in PCa.