Lung adenocarcinoma (LUAD)-derived exosomal circRNA_101093 (cir93) increases fatty acid-binding protein 3 (FABP3) to reduce global arachidonic acid through reactions with taurine, thus inducing ferroptosis by desensitizing LUAD cells and decreasing total lipid peroxidation. Here, FABP3 is linked to lung adenocarcinoma.