CRISPRi suppression of NF2 in HEI-193 cells stably expressing dCas9-KRAB14,40 promoted cell proliferation compared to HEI-193 cells expressing non-targeted control sgRNAs (sgNTC) (Supplementary Fig. 13k, l), suggesting NF2 retains tumor suppressor functionality in this cell line. This evidence concerns the gene NF2 and neoplasm.