PTGDS and neoplasm: Shared tumor cell clusters were distinguished by expression of Hedgehog signaling (C0, PTCH1), immature Schwann cell (C1, PDGFRA), extracellular matrix (C3, LUM), growth factor signaling (C4, FGFR1), non-myelinating Schwann cell (C6, NGFR), mesodermal (C7, SFRP4), cell proliferation (C9, MKI67, TOP2A), and steroid signaling genes (C11, PTGDS) (Fig. 1d and Supplementary Fig. 4b).