FBXO31 and pachyonychia congenita: To investigated the expression profile of FBXO31 in pancreatic adenocarcinoma (PAAD), which constitutes 90–95% of PC, we analyzed TCGA and GTEx clinical datasets, including 179 cases of PAAD tissues and 171 cases of adjacent normal tissues (167 cases from GTEx and 4 cases from TCGA).