INS and diabetes mellitus: Notably, the benefits associated with educating patients with lipohypertrophy on injection technique are not only limited to improving health outcomes but also result in cost savings in diabetic care, including insulin costs and treatment of diabetes complications.55 Obtained results indicate the significance of the issue of lipohypertrophy and the necessity to adhere to FITTER guidelines regarding proper injection technique, including the importance of avoiding injections in areas affected by lipohypertrophy, proper site rotation, and needle single-use.9