NEDD4 and idiopathic pulmonary fibrosis: In GSE47460 (GPL6480), the ROC curves demonstrated that CDKN2A, NEDD4, and CDKN2A + NEDD4 were effective in distinguishing IPF from normal individuals, with AUC values of 0.799, 0.802, and 0.799 (Fig. 8C–E).