IL1B and deep vein thrombosis: This may lead to chronic inflammation of the vascular wall.[48,49] Chronic inflammation in the blood vessel wall can also affect the ability of thrombotic substances to adhere in the peripheral venous system,[50] increasing the risk of DVT.[51,52] The development of chronic inflammation is significantly influenced by important inflammatory mediators like IL1B and IL6.[53] Our PPI analysis results are consistent with these processes (IL1B, IL6), indicating their crucial role in DVT development.