By comparing the gene expression of STK3, C9orf78 and STRN3 in tumour tissue with respect to their non-malignant counterparts, we found that the STK3, C9orf78 and STRN3 gene were differently expressed among the SNC histotypes, showing low expression in SNADC (ITAC), SNUC and SNEC, while high expression of these genes was found in SNSCC and SNACC. Here, C9orf78 is linked to neoplasm.